KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN5
All Species:
26.97
Human Site:
T353
Identified Species:
53.94
UniProt:
O15484
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15484
NP_004046.2
640
73169
T353
S
H
L
S
I
H
K
T
W
E
E
A
R
L
H
Chimpanzee
Pan troglodytes
XP_001146965
641
74541
L353
P
I
F
G
R
K
E
L
E
S
V
L
G
C
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542293
640
73142
T353
S
Y
L
S
V
H
K
T
W
E
E
A
R
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O08688
640
72936
T353
S
Y
L
S
I
H
K
T
W
E
E
A
R
L
H
Rat
Rattus norvegicus
Q8R4C0
640
73046
T353
S
Y
L
S
I
H
K
T
W
E
E
A
R
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518356
408
46381
S149
G
G
C
I
N
H
K
S
T
F
L
Q
N
P
Q
Chicken
Gallus gallus
Q92177
810
93542
Q420
T
L
E
A
D
K
L
Q
T
W
T
V
S
V
N
Frog
Xenopus laevis
NP_001080808
642
73235
T353
S
Y
L
S
I
Y
K
T
W
E
E
A
V
L
R
Zebra Danio
Brachydanio rerio
XP_001345114
642
73723
T353
S
Y
L
S
I
H
K
T
W
E
E
E
V
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
N397
S
L
T
E
D
Q
Q
N
S
G
K
R
K
W
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22036
648
73596
S363
S
V
F
S
F
S
R
S
Y
D
E
Q
I
V
F
Sea Urchin
Strong. purpuratus
XP_792213
642
72430
T354
T
Y
L
S
L
Q
R
T
W
H
E
S
L
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
N.A.
92
N.A.
92.1
90.6
N.A.
51.4
30.8
73.9
71.6
N.A.
30.7
N.A.
40.1
47.6
Protein Similarity:
100
65.5
N.A.
95.6
N.A.
96
94.8
N.A.
57.3
46.9
86.2
83.8
N.A.
45.2
N.A.
57.2
64.9
P-Site Identity:
100
0
N.A.
80
N.A.
93.3
86.6
N.A.
13.3
0
73.3
66.6
N.A.
6.6
N.A.
20
33.3
P-Site Similarity:
100
6.6
N.A.
93.3
N.A.
100
93.3
N.A.
20
26.6
86.6
80
N.A.
26.6
N.A.
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
42
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
17
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
9
9
0
0
9
0
9
50
67
9
0
0
9
% E
% Phe:
0
0
17
0
9
0
0
0
0
9
0
0
0
9
9
% F
% Gly:
9
9
0
9
0
0
0
0
0
9
0
0
9
0
0
% G
% His:
0
9
0
0
0
50
0
0
0
9
0
0
0
0
17
% H
% Ile:
0
9
0
9
42
0
0
0
0
0
0
0
9
0
9
% I
% Lys:
0
0
0
0
0
17
59
0
0
0
9
0
9
0
0
% K
% Leu:
0
17
59
0
9
0
9
9
0
0
9
9
9
42
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
0
0
0
9
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
17
9
9
0
0
0
17
0
0
9
% Q
% Arg:
0
0
0
0
9
0
17
0
0
0
0
9
34
0
34
% R
% Ser:
67
0
0
67
0
9
0
17
9
9
0
9
9
0
0
% S
% Thr:
17
0
9
0
0
0
0
59
17
0
9
0
0
0
0
% T
% Val:
0
9
0
0
9
0
0
0
0
0
9
9
17
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
59
9
0
0
0
9
9
% W
% Tyr:
0
50
0
0
0
9
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _